Matrix Games Forums

One thing I found that helped me (with a widescreen monitor) was to move the Windows Bar to the right edge of the screen, freeing up the bottom. The right edge is where the game has the fewest icons to click on (only off-map pinpoints really).
I also vaguely recall someone saying they could not use Alt-Tab from within the game when using their laptop, but that may have been with a forced full screen rather than a window for the game.