Yes! As you know, historically the Germans drove on three objectives simultaneously. Often an experienced player will concentrate on two or even one area in order to gain what seems like better than historical results. However, note that all [and I mean ALL, that I have seen] of those AAR's end early in favor of the Soviets.the PO can really hammer you if you make a wrong step?
During play-testing we tried concentrating on the big three [Leningrad, Moscow, Stalingrad] one at a time. All Fails. There just aren't enough Axis troops to hold the line while being strong enough locally, as it was historically.
I should say that while it is definitely possible to take one of the three before the first winter, it is quite difficult to hold it.
My favorite strategy is to go at Leningrad initially while keeping a fair effort in the center and south. It's a juggling act but if you stay focused you should be able to get Leningrad. This allows you to actually shorten the front for the winter and spend it R&R'ing for a combined AGN/AGC attack on Moscow in spring 1942. Then into the south in 1943.
P.S. I believe the above strategy is very viable because, in my opinion, Hitler bungled the campaign by stopping/starting AGN and AGC several times, while wastefully moving units willy-nilly back and forth between the two AG's to no effect. Of course, the rookie D21 / RGW player may make the same mistakes.

